- ... three RCTs 73 , 117 , 131 , and a prospective cohort 185 ): Different doses of aripiprazole are probably of little or no ... synthesis below focuses on the differences between these doses. The cohort study 185 (N = 21) investigated three high doses ( ...
- ... elevated bleeding risk above baseline. In one large cohort study, low-dose ASA significantly increased rates of hospitalization for bleeding ... results stratified by medication use. In the large cohort study that compared low-dose ASA users to propensity-score matched never-users, ...
- ... both groups and 45–50 in the Stein cohort study. The rFVIIa dose range of 40–200 μg/kg in the ... received just one dose. Patients in the Gelsomino cohort 121 received the lowest doses of rFVIIa in all of the cohort studies, ...
- ... not reached. RR was similar in the two-dose cohorts, with fewer adverse events at the lower dose, leading to FDA approval of the 200-mg ... infusion administered every 3 weeks) of the trial dose given as 3 mg/kg IV over 30 ... I expansion cohort trial ( NCT02383212 ) that required patients to have at ...
- NLM Digital Collections - Proton beam therapy : final evidence reportPublication: [Boston, MA] : Institute for Clinical and Economic Review, [2014]... DCH, Grade I: 43% therapeutic Study Objective Overall cohort • Dose: 16-30 Gy, of PBT vs. photon modality ...
- ... many of these factors in a relatively unselected cohort of new low-dose ASA users matched to controls. Although ASA exposures ... of low-dose ASA within their study designs. Cohort studies either restricted to a single low-dose, 86 did not evaluate dosage effects within the ...
- ... meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age. Neuro Oncol 21 ( ... at cancer diagnosis and higher mean pancreatic tail dose. St. Jude Lifetime Cohort investigators evaluated the prevalence of and risk factors ...
- NLM Digital Collections - Abuse-deterrent formulations of opioids : effectiveness and value : final evidence reportPublication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, August 8, 2017... to 60mg and 90mg in up to two cohorts. Dose determination based on drug liking bipolar VAS. Drug ... years; enrolled Opioid dispensing rate, mg morphine equivalent dose per JAMA 2015 72 ... using an open cohort 3) other long acting used Optum data which ...
- ... greater with increasing duration of use, but not dose. Two cohort studies supplemented information from RCTs. Table 1 Effect ... of use could not be separated. 161 Three cohort studies presented CRC risk according to daily aspirin dose. The observational component of the WHI study found ...
- NLM Digital Collections - Spinraza and Zolgensma for spinal muscular atrophy : effectiveness and value : final evidence ...Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, May 24, 2019... Zolgensma. This Executive Summary focuses on the high-dose cohort only; results from the low-dose cohort are described in Section 3. We did not ... results from the 12 infants in the high- dose cohort. Baseline Characteristics of Key Trials Key baseline characteristics ...
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