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  1. Colon Cancer Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65858
    ... patients after surgical resection of liver metastases. The study closed because of poor accrual, and a combined analysis of the study and the FFCD-9902 study was done instead. ...
  2. Pancreatic Cancer Treatment (Adult) (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65957
    ... 8 ][ Level of evidence: 3iA ] With a target accrual of 128 patients, the study closed prematurely because of slow accrual. After a median follow-up of 8.8 ...
  3. Rectal Cancer Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65965
    ... the intended sample size was 900 patients, the study with 267 patients closed early because of poor accrual.[ 4 ][ Level of evidence: 1iiA ] With a median ...
  4. Breast Cancer Treatment (Adult) (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65744
    ... the physician's choice or no chemotherapy. The study was closed early because of poor accrual. The original sample size for a hazard ratio (HR) of 0.74 was 977 patients (347 DFS events) and was revised subsequently to 265 ... time of study closure.[ 12 ][ Level of evidence: 1iiDii ] In ER- ...
  5. NLM Digital Collections - An evidence-based health care system : the case for clinical trials registries : Office of ... 
    Publication: [Bethesda, Md. : Office of Medical Applications of Research?, 1993]
    resource.nlm.nih.gov/101120654
    ... title, starting date, last date of projected support, study status (planning, open, or closed), age range of population, projected sex/size of ...
  6. Antineoplastons (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65872
    ... reach agreement on proposed changes to increase patient accrual and dose , these agreements could not be reached, and the studies were closed prematurely in August 1995.[ 1 , 2 ] The developer ...
  7. Laryngeal Cancer Treatment (Adult) (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65746
    ... 5 Gy/30 fractions for T2).[ 10 ] The study was underpowered and closed early because of a lack of accrual, although no statistically significant differences were seen between ...
  8. Prostate Cancer Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK66036
    ... comorbidity, or locally advanced disease (11% of the study population). Planned accrual was 750 patients, but because of slow accrual, the trial closed at 293 patients. In groups 1 and 2 ...
  9. NLM Digital Collections - AIDS Tracer M, 2/3/1987-3/27/1987 
    https://resource.nlm.nih.gov/101637321X38
    ... in the frequency of opportunistic infections and performance status in patients on both arms of the study. After deliberations in a closed session, the DSMB requested BW to provide the ...
  10. NLM Digital Collections - Management of adult testicular germ cell tumours : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), March 2011
    resource.nlm.nih.gov/101609344
    ... possible alternate to cisplatin, but an MRC randomised study of 130 patients who received either carboplatin or etoposide and cisplatin was closed prematurely due to poor accrual. Data showed an inferior disease-free survival for ...
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