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  1. Chronic Myeloid Leukemia Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65916
    ... in situ hybridization (FISH) . FISH of the BCR :: ABL translocation can be performed using the bone marrow aspirate ... count, splenomegaly, thrombocytosis, and identification of the BCR :: ABL translocation.[ 1 ] Table 1. Treatment Options for CML Phases ...
  2. Childhood Chronic Myeloid Leukemia Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK602707
    ... Chronic myeloid leukemia (CML) results from the BCR :: ABL translocation. CML is primarily an adult disease but represents ...
  3. Myeloproliferative Neoplasms Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65852
    ... absence of the Philadelphia chromosome or the BCR :: ABL translocation. Identification of a JAK2 , MPL , or CALR variant ( ...
  4. NLM Digital Collections - Drugs against cancer : stories of discovery and the quest for a cure 
    Publication: Bethesda, Maryland : National Cancer Institute, [2022]
    resource.nlm.nih.gov/9918505188606676
    ... disease discussed in Chapter 14, where a BCR-ABL translocation drives the overexpression oftheABL oncogene. In 1999, Claudia ...
  5. Childhood Cancer Genomics (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK374260
    ... variants associated with a subset of medulloblastoma cases. ABL family genes activated by translocation in a subset of acute lymphoblastic leukemia (ALL) ...
  6. NLM Digital Collections - Tumor Viruses and Oncogenes 
    Publication: Produced: [1973-1984]
    resource.nlm.nih.gov/101584926X300
    ... Alteration c-myc Burkitt's lymphoma Translocations Plasmacytoma e~-abl Myeloid leukemia Translocation (Philadelphia chromosome) c-myc Myeloid leukemia Amplification Apudoma ...
  7. NLM Digital Collections - The Molecular Genetics of Cellular Oncogenes 
    Publication: Annual Reviews, Inc., 1984
    resource.nlm.nih.gov/101584926X272
    ... A., et al. 1983. Localization of the c-abl oncogene adjacent to a translocation breakpoint in chronic myelocytic leukaemia. Nature 306:239- ... Evidence for a common ancestor to src and abl cellular genes. Cell ... 1984. A variant translocation places the im- munoglobulin genes 3' to the ...
  8. Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK65763
    ... have been noted to have a series of translocations involving tyrosine-kinase encoding ABL-class fusion genes, including ABL1 , ABL2 , CSF1R , and ...
  9. BCR-ABL1 Genetic Test: MedlinePlus Medical Test 
    https://medlineplus.gov/lab-tests/bcr-abl1-genetic-test
    ... mutations or variants . Other names: BCR-ABL , BCR-ABL fusion, Philadelphia chromosome, B-cell acute lymphoblastic leukemia (B-ALL), chronic myelogenous leukemia (CML), t(9;22), BCR-ABL1 Transcript Detection by RT-PCR, Quantitative BCR-ABL1 Translocation Detection by RT-PCR What is it used ...
  10. Chronic myeloid leukemia 
    https://medlineplus.gov/genetics/condition/chronic-myeloid-leukemia
    ... Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med. 1996 ... Chromosome Translocations on the Clinical Course of Chronic Myeloid Leukemia. ...
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