... activation domain. It also contains a C-terminal coiled-coil domain and ezrin- radixin moesin (ERM) domain. Mutations in the TSC1 gene are associated with TUBEROUS SCLEROSIS. Parent Heading: Intracellular ...

... activation domain. It also contains a C-terminal coiled-coil domain and ezrin-radixin moesin (ERM) domain. Mutations in the TSC1 gene are associated with TUBEROUS SCLEROSIS. Tree locations: Intracellular ...

... N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four ... domains, one of which is a RING FINGER DOMAIN, a coiled-coil region, and a highly variable C-terminal region. ...

... receptors. They are characterized by an amino-terminal coiled-coil domain, a linker region, and a carboxy-terminal FIBRINOGEN- ...

... et al., 2016) . Unliganded TRAP1 N forms a domain-swapped coiled coil that allows the dimer to close partially. A recent model sug- gests that adding ATP to this partially closed conformation allows TRAP1 to form a fully closed domain-swapped b -strand conformation, fostering chaperone activity ( Sung ...