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194 results
  1. pdfMany dissimilar NusG protein domains switch between α-helix and β-sheet folds 
    https://www.nlm.nih.gov/.../porter/pdfs/sequence_space_final.pdf
    ... variant #4), and an annotated “ NGN domain- containing protein ” (variant #5). Interestingly, all fi ve of these variants ... though without experimental validation. Also, “ NGN domain-containing protein ” variant #5 is genomically inconsistent with being a NusG ...
  2. Successful NCBI-NIAID Codeathon Explored VCF Files in Population Genomics - NCBI Insights 
    https://ncbiinsights.ncbi.nlm.nih.gov/...i-niaid-codeathon-vcf-files
    ... FASTA files, informing future variant forecasts.  VCF Spike Protein Variants and ACE2 Population Frequencies Visualized relationships between Spike protein and ACE2 receptor variants, offering insights into viral entry and susceptibility.  Minor ...
  3. dbSNP human build 154 release + ALFA data - NCBI Insights 
    https://ncbiinsights.ncbi.nlm.nih.gov/...build-154-release-alfa-data
    ... features include: dbSNP search now support HGVS and protein variant search RefSNP page linked to Litvar information Filter ...
  4. Making Custom Databases for Web BLAST - NCBI Insights 
    https://ncbiinsights.ncbi.nlm.nih.gov/...tom-databases-for-web-blast
    ... of psiblast searches on a giant dataset of protein variants, and it is both A) impractical to handle this remotely, and B) a goal of the project to do the computational work on ... to pare my local BLAST nr protein DB down to just the taxa of interest. ...
  5. pdf2017MeshTreesWithChangesShown.pdf 
    https://www.nlm.nih.gov/.../2017MeshTreesWithChangesShown.pdf
    ... Core Proteins Antigens, Plant Antigens, Protozoan Merozoite Surface Protein 1 Variant Surface Glycoproteins, Trypanosoma Antigens, Surface Antigens, Differentiation Antigens, ...
  6. pdfkim_structure_2021.pdf 
    https://www.nlm.nih.gov/.../labs/porter/pdfs/kim_structure_2021.pdf
    ... simulations to accurately predict the struc- tures of protein G variants with up to 98% sequence identity but very ... Kern, D. (2007). A hierarchy of timescales in protein dynamics is linked to enzyme ... (2016). Cryo-EM structure of aerolysin variants reveals a novel pro- tein fold and the ...
  7. pdfFixJ_KdpE_full_final.pdf 
    https://www.nlm.nih.gov/.../porter/pdfs/FixJ_KdpE_full_final.pdf
    ... switch the fold and function of an engineered protein G variant from a 3- a -helix bundle that binds human serum albumin to an a / b -plait fold that binds ... may be one mechanism by which new protein folds originated in nature. If so, this evolutionary ...
  8. pdf2015 National Library of Medicine Informatics Conference Agenda Book 
    https://www.nlm.nih.gov/..._Informatics_Training_Conference_Book.pdf
    ... Kurt Weiss/Wisconsin 7. In-Depth Identification of Protein Sequence Variants and Postranslational Modification in 10 Human Cell Lines - ...
  9. How do I obtain a transcript and protein sequence for a gene by using the NCBI Gene database? · NLM Customer Support ... 
    https://support.nlm.nih.gov/knowledgebase/article/KA-03361/en-us
    ... Protein record if there are known transcript splice variants/protein isoforms for the gene. Select the record (for ... itself ( example ). The steps for accessing the RefSeq protein sequences are the ... genes that have transcript variants, select the variant that you want and click ...
  10. Gene filtering in NCBI Sequence Viewer - NCBI Insights 
    https://ncbiinsights.ncbi.nlm.nih.gov/.../08/20/gene-filtering-in-sv
    ... non-coding transcripts, including pseudogenes, so that only protein-coding transcript variants are shown in your view. You can also ... Ensembl genes track filtered to show only transcript variants that encode a protein validated by the CCDS project is shown below: ...
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