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  1. Saccharomyces Boulardii 
    https://medlineplus.gov/druginfo/natural/332.html
    Saccharomyces boulardii (S. boulardii) is a type of probiotic ("friendly" organism). It's a yeast that is actually a strain ... Insufficient Evidence to Rate. The effectiveness ratings for SACCHAROMYCES BOULARDII are as follows: Diarrhea. Taking S. boulardii by mouth ...
  2. Evidence Tables - Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection - NCBI ... 
    https://www.ncbi.nlm.nih.gov/books/NBK83518
    ... disease: use of high-dose vancomycin combined with Saccharomyces boulardii. Clinic Infect Dis. 2000 Oct; 31 (4):1012– ... et al. A randomized placebo-controlled trial of Saccharomyces boulardii in combination with standard antibiotics for Clostridium difficile ...