- ... FOLFOX with or without bevacizumab, but this trial closed because of poor accrual; ... that combined oxaliplatin with fluoropyrimidine-based chemoradiation therapy ...
- ... 5 Gy/30 fractions for T2).[ 10 ] The study was underpowered and closed early because of a lack of accrual, although no statistically significant differences were seen between treatment arms in terms of local progression-free survival ( ...
- ... P = .13). The European Organization for Research and ... study closed because of poor accrual, and a combined analysis of the study and ...
- ... reach agreement on proposed changes to increase patient accrual and dose , ... as a clinical therapy against several different types of cancer, alone or ...
- ... asymptomatic men who were considered unsuitable for curative treatment because of age, comorbidity, or locally advanced disease (11% of the study population). Planned accrual was 750 patients, but because of slow accrual, the trial closed at 293 patients. In groups 1 and 2 ...
- ... radiation followed by gemcitabine.[ 17 ] Of note, the study was closed early as ... for combined modality therapy (one-sided P = .017 by stratified log-rank ...
- ... 0.41–0.58; P < .00001). In this study, the number needed to treat with radiation ... closed because of poor accrual (636 of planned 1,790 patients accrued). Patients ...
- ... treatment(s) in order to establish comparative effectiveness studies between multiple treatments. A greater emphasis on baseline covariate data may ... care can significantly impact the design of a study as new treatments are approved or new patient populations become of ...
8 results