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12 results
  1. ... are variants acquired during a person's lifetime and present only in certain cells. The somatic ... Additional Information & Resources Genetic ...
  2. ... X-Linked Neutropenia (XLN) Males with XLN typically present with congenital neutropenia associated with myelodysplasia, increased myeloid cell apoptosis, and lymphoid cell abnormalities. Beel & Vandenberghe [2009] described two males ...
  3. ... marrow, and sometimes fragments of megakaryocytic nuclei are present in the blood, ... and the myeloid/erythroid ratio in the marrow is usually greatly ...
  4. ... a background of inflammatory cells consisting of small lymphocytes, ... represent a clonal population. Almost all cases of Hodgkin lymphoma arise ...
  5. ... phagocytic system. Only Langerhans cell histiocytosis (LCH), a myeloid-derived ... and, occasionally, multinucleated giant cells.[ 2 , 3 ] The ...
  6. ... myeloid leukemia.</html:p><html:p >The rapid myeloid and lymphoid cell production caused by these cancers results in enlargement ... synonym><synonym >8p11 stem cell syndrome</synonym><synonym >Myeloid ... cell leukemia/lymphoma</synonym></synonym-list><db-key-list >< ...
  7. ... anomalies. Progressive bone marrow failure with pancytopenia typically presents in the first decade, often initially with thrombocytopenia or leukopenia. The incidence of acute myeloid leukemia is 13% by age 50 years. Solid ...
  8. ... mutations acquired during a person's lifetime that are present only in certain cells. The somatic mutation occurs initially in a single cell, which continues to grow and divide, producing a group of cells with the same mutation (a clonal population). The most common genetic abnormality in PDGFRA - ...
  9. ... gene.[ 17 ] Topoisomerase II inhibitor–related t-AML presents as overt leukemia after a ... Myeloid Malignancies Treatment for more information.) ...
  10. ... individuals with SDS may develop certain characteristic cytogenetic clonal changes, such as del(20)(q11) and i( ... in bone marrow, w/distinct cytoplasmic vacuolization in myeloid precursors mtDNA contiguous- gene deletions/duplications SPINK1 -related ...
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