... does not require reporting of results for interventional clinical studies ... registration and sponsor/investigators perception of registry purpose, thus ...

... included, and controls were selected from the Civil Registration System. Neither case/control status nor use of statins was likely to be ... and radiation therapy. Linkage with the Danish Civil Registration System provided data on vital status; linkage with the Danish National Patient Registry provided ...

... individuals stratified by diagnostic test result and disease status). For all studies, EPC investigators extracted data elements using standardized operational definitions (e. ...

... with prolonged PFS. The authors concluded that MMR status predicted clinical benefit to immune checkpoint blockade with pembrolizumab. A single-arm phase 2 study ( CheckMate 142 ) of another PD-1 inhibitor, nivolumab, ...

... of patient performance status Physicians evaluate patient performance status (PS) in determining prognosis and in making treatment decisions. Investigators compared the Eastern Cooperative Oncology Group PS reported ...

... of equipoise. An alternative view, referred to as “clinical equipoise,” is that equipoise can be achieved at the group level, with the enthusiasm of some investigators for the prospects of the study intervention being balanced by the skepticism of others. ...

... androgen-signaling therapy versus chemotherapy. Multiple genetically informed clinical trials are under way ... in own window Study Cohort Germline Results ...

... risk of hereditary ovarian cancer. Hereditary Ovarian Cancer Clinical Study Group. N Engl J ... Women's Health Initiative Investigators: Risks and benefits of estrogen plus progestin in ...

... s health initiative randomized controlled trial. Journal of Clinical Oncology. ... study in an Australian community. Journal of Investigative Dermatology. ...

... each study that met inclusion criteria, a single investigator abstracted information on study design, year, setting (field or ED), country, sample size, eligibility criteria, population and clinical characteristics (age, sex, race, type of opioid involved ...