- ... joins a group of other pediatric entities with activating BRAF mutations, including select nonmalignant conditions (e.g., benign nevi) [ ... Quispel W, Badalian-Very G, et al.: Somatic activating ARAF mutations in Langerhans cell ... somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in ...
- ... Dougherty MJ, Santi M, Brose MS, et al.: Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas. ...
- ... estimated 25% of anaplastic thyroid cancers harbor an activating BRAF (V600E) mutation.[ 8 ] Evidence (dabrafenib and trametinib): A phase II ...
- ... Dematteo RP, Besmer P, Antonescu CR. Novel V600E BRAF mutations in imatinib-naive ... activating mutations in gastrointestinal stromal tumors. Science. 2003 Jan ...
- ... Yamamoto GL, Kozakewich HP, Warman ML. Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. Am J Hum ... overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA. Nat Genet. 2012; 44 :928–33. [ ...
- ... Vogelstein B, Meyerson M, Sellers WR, Neel BG. Activating mutations of the Noonan syndrome-associated SHP2/PTPN11 gene ... Cavé H, Gelb BD, Neel BG, Tartaglia M. Activating mutations affecting the Dbl homology domain of SOS2 cause ...
- ... harbor wild types of KRAS (i.e., lack activating mutations at codon 12 or 13 of the KRAS ... KRAS exon 2 status for other KRAS and BRAF mutations.[ 83 ][ Level of evidence: 3iiiA ] Of the 620 ...
- ... harbor wild types of KRAS (i.e., lack activating mutations at codon 12 or 13 of the KRAS ... 2 wild-type status for other KRAS and BRAF mutations.[ 43 ] Level of evidence: 3iiiA Of the 620 ...
- ... HRAS mutations in Costello syndrome: detection of constitutional activating mutations in codon 12 and 13 and loss of ... K, Kure S, Matsubara Y. Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome. Nat Genet. 2006; ...
- ... unless there is hemorrhage into the tumor. Somatic activating mutations of GNAQ and GNA11 have been found to ... UM, Couto JA, Hann S, et al.: Somatic Activating Mutations in GNAQ and GNA11 Are Associated with Congenital ...
20 results