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86 results
  1. ... to a Second Single Antihypertensive Agent Used as Monotherapy for Hypertension after Failure of the Initial Drug ... to a Second Single Antihypertensive Agent Used as Monotherapy for Hypertension after Failure of the Initial Drug ...
  2. ... on the comparative effects of combination therapy and monotherapy. That trial, which aims to enroll 2,400 ... cisco presented results of a study of ddI monotherapy in 160 HIV-infected people. They found that ...
  3. NLM Digital Collections - Chronic hepatitis C virus infection : developing direct-acting antiviral drugs for treatment 
    Publication: Silver Spring, MD : Center for Drug Evaluation and Research, November 2017
    ... data from clinical trials (e.g., short-term monotherapy trials, dose- finding trials in combination with other ... should be a repeat- dose, randomized, dose-ranging, monotherapy trial with collection of intensive PK, safety, and ...
  4. NLM Digital Collections - Poly ADP-ribose polymerase (PARP) inhibitors for ovarian cancer : effectiveness and value : ... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, September 28, 2017
    ... first-line carboplatin and paclitaxel, followed by bevacizumab monotherapy as maintenance therapy, prolonged progression-free survival (PFS) ... Forms & Approval Month Duration Strengths (USD)* Olaparib 1) Monotherapy for patients 300 mg BID (PO) Tablets: 1) ...
  5. NLM Digital Collections - Targeted immune modulators for rheumatoid arthritis : effectiveness and value : evidence ... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, April 7, 2017
    ... often as every 4 weeks Abatacept Use as monotherapy or with DMARDs Subcutaneous or 12/27/2005 $ ... or 1/8/2010 $898 per (Actemra®, Genentech) monotherapy, start with 4 mg/kg every Intravenous (iv) ...
  6. NLM Digital Collections - Controversies in the management of patients with type 2 diabetes : final report 
    Publication: [Boston, MA] : Institute for Clinical and Economic Review, December 2014
    ... in patients with inadequate glycemic control on metformin monotherapy or the combination of metformin and a sulfonylurea, ... in patients with inadequate glycemic control on metformin monotherapy or the combination of metformin and a sulfonylurea, ...
  7. NLM Digital Collections - Obeticholic acid for the treatment of primary biliary cholangitis : comparative clinical ... 
    Publication: Boston, MA : Institute for Clinical and Economic Review, March 2016
    ... with an inadequate response to UDCA, or as monotherapy in adults unable to tolerate UDCA.12,13 ... with an inadequate response to UDCA, or as monotherapy in patients intolerant to UDCA, relative to standard ...
  8. NLM Digital Collections - Modulator treatments for cystic fibrosis : effectiveness and value 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, April 27, 2020
    ... Value Life Years* Population 1 - Eligible for Kalydeco Monotherapy Only BSC $2,319,000 15.83 21. ... Per PEx Averted Population 1 - Eligible for Kalydeco Monotherapy Only Kalydeco Plus BSC $1,370,000 $1, ...
  9. NLM Digital Collections - Diagnosis and management of epilepsy in adults : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), 2018
    ... start antiepileptic ... ...
  10. NLM Digital Collections - Management of hepatitis C : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), July 2013
    ... 1- markers of iron excess prior to IFN monotherapy may improve the SVR.114, 115 DModest iron ... the renal failure.164 Treatment with pegylated IFN monotherapy at a dose of 135 µg subcutaneously 1 + ...
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