... see section 14.4). The epidermal growth factor receptor (EGFR) antibodies ... 13 of the KRAS gene are insensitive to EGFR inhibitors.181 Although the ...

... other genes, ¢.g., the thyroid-stimulating hormone (TSH) gene, that are ... (17). Recently, two types of TR mutated mice, i.e., “knockout” and “ ...

... the NIH/3T3 cell assay Examples of cell types in which Genes transforming activity is found* References c-Ha-ras1 Bladder carcinoma ... genetic alteration that most commonly explains the transforming activity of ... mutant ras genes to validate the functional significance of the identi- ...

... binding to a specific receptor called natriuretic peptide receptor-B that reduces the growth regulation gene's activity and stimulates bone growth. The FDA granted the ...

... a signal ema- nating from the T-cell receptor complex that induces IL-2 gene transcription. Type 1 human immunodeficiency virus (HIV-1) contains seven ...

... of function mutation was found in the PCSK9 gene that increases its activity, lowers LDL-receptor density, and causes high levels of LDL-C. ...

... a plasmid, pBC29, which car- ries the ppk gene, the catalase activity was restored to the wild-type level. However, these catalase activity measurements Strain (U/ ...

... T; Tsuru S; Yoshida M. Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1. EMBO J 1986 Nov;5(ll):2883- ...

... interpret practically all known forms of antigen-antibody activities. Three types or orders of receptors are assumed. The first order supplies only the ...

... above). Such viruses will be tested for biological activity in ransformation assays and for use as radioactive ligands for Wnt receptors. (v) Armadillo, a gene that acts downstream of wingless in the fly, ...