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13 results
  1. NLM Digital Collections - Controversies in migraine management : a technology assessment : final report 
    Publication: [Boston, MA] : Institute for Clinical and Economic Review, August 19, 2014
    resource.nlm.nih.gov/101642254
    ... for Clinical and Economic Review, 2014 Page 5 topiramate), anti-depressants (amitriptyline, venlafaxine), angiotensin-converting enzyme inhibitors ( ... be discussed below. Three randomized trials found that topiramate was significantly more effective than placebo in reducing ...
  2. NLM Digital Collections - Controversies in obesity management : a technology assessment : final report 
    Publication: [Boston, MA] : Institute for Clinical and Economic Review, August 10, 2015
    resource.nlm.nih.gov/101666737
    ... Not significant OR Odds ratio P/T Phentermine/topiramate PHQ-9 Patient Health Questionnaire PMPM Per-member ... 25) Harms Quality of life Naltrexone/bupropion Phentermine/topiramate Complications Medications extended-release extended-release Revisions Lorcaserin ...
  3. NLM Digital Collections - Calcitonin gene-related peptide (CGRP) inhibitors as preventive treatments for patients with .... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, July 3, 2018
    resource.nlm.nih.gov/101744957
    ... venlafaxine), anti-seizure medications (divalproex sodium, sodium valproate, topiramate), and beta-blockers (propranolol, metoprolol).16 Patients with ... chronic migraine populations, commonly- used preventive therapies included ... propranolol, and amitriptyline. For chronic migraine, onabotulinum toxin ...
  4. NLM Digital Collections - Diagnosis and management of epilepsy in adults : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), 2018
    resource.nlm.nih.gov/101671140
    ... is as effective and better tolerated than carbamazepine, topiramate, or oxcarbazepine.86, 88 There is evidence from ... GENERALISED EPILEPSIES In genetic generalised epilepsies, sodium valproate, topiramate and lamotrigine may be used.87, 97 Of ...
  5. NLM Digital Collections - Pharmacological management of migraine : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), February 2018
    resource.nlm.nih.gov/101730373
    ... headache frequency did not differ between propranolol and topiramate. Propranolol was 1++ better than nifedipine but there ... Three systematic reviews reported on the efficacy of topiramate compared to placebo in patients with episodic and ...
  6. NLM Digital Collections - Epilepsies in children and young people : investigative procedures and management : a ... 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), May 2021
    resource.nlm.nih.gov/9918334378406676
    ... clobazam, gabapentin, lamotrigine, levetiracetam, | oxcarbazepine, sodium valproate or topiramate can be offered as adjunctive treatment if first- ... Carbamazepine, clobazam, gabapentin, lamotrigine, levetiracetam, oxcarbazepine, sodium valproate, topiramate or zonisamide (over 6 years of age) can ...
  7. NLM Digital Collections - S5(R3) detection of reproductive and developmental toxicity for human pharmaceuticals 
    Publication: Silver Spring, MD : Center for Drug Evaluation and Research, May 2021
    resource.nlm.nih.gov/9918350987506676
    ... X Tacrolimus X X Thalidomide X X X Topiramate X X X Tretinoin (all-trans-retinoic acid) ... of 180 mg/kg.] 100 Contains Nonbinding Recommendations TOPIRAMATE CAS No.: 97240-79-4 Rat Rat Rat ...
  8. NLM Digital Collections - Management of schizophrenia : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), March 2013
    resource.nlm.nih.gov/101609432
    ... who are experiencing weight gain on antipsychotic medications. Topiramate A systematic review included five RCTs of topiramate for the prevention or treatment of weight gain ...
  9. NLM Digital Collections - Management of chronic pain : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), December 2013
    resource.nlm.nih.gov/101671099
    ... No evidence was found on the efficacy of topiramate for the treatment of patients with chronic pain. ... pregabalin c. sodium valproate d. carbamazepine/ oxcarbazepine e. topiramate f. lamotrigine g. lacosamide h. levetiracetam 9. In ...
  10. NLM Digital Collections - Part D plans generally include drugs commonly used by dual eligibles : 2018 
    Publication: [Washington, D.C.] : U.S. Department of Health and Human Services, Office of Inspector General, June 2018
    resource.nlm.nih.gov/101738033
    ... 1,849,180–3,149,233 386 100% Topiramate 768 2,497,034 1,765,504–3, ...
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