- NLM Digital Collections - Diagnosis and management of colorectal cancer : a national clinical guidelinePublication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), August 2016... 161 In younger patients, regimens combining oxaliplatin with thymidylate synthase (TS) inhibition (capecitabine, 1+ ++ 5-Fluorouracil/folinic acid) may be more effective than TS inhibitors alone.162 Combined treatment is more toxic 1 ...
- NLM Digital Collections - Review of intramural research (1965)Publication: [Bethesda, Md.] : U.S. Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health... cells, i.e., the enzymatic con- version of thymidylate (TMP) to high-energy phosphorylated forms by the ... syndrome was found to lack the enzyme cystathionine synthase in her liver and deficiency of this en- ...
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