... signaling pathways include downstream GTPases encoded by RAS genes. Some 15%-30% of lung adenocarci- nomas contain activating mutations in the RAS family member KRAS. These mutations are most frequently found ...

... c-myc, ins-2, and members of the ras family (Berenson et al. 1989, Bos ... point mutation—in a gene encoding a proto-oncogene is enough to transform ...

... c-myc, ins-2, and members of the ras family (Berenson et al. 1989, Bos ... point mutation—in a gene encoding a proto-oncogene is enough to transform ...

... the mutant "transforming" genes, all members of the ras gene family thus far (Table 4), have been cloned in ... be thought to have undergone a variety of "activating" events: ... gene that transforms cultured cells; or insertion mutation, amplification, ...

... those cases where there are no other affected family members, blood specimens wiU be obtained to study specific gene mutations when the specific gene or genes for Usher's ...

... immunogenetics QW 541 Special topics, by subject Genes, ras QZ 202 Genes, Regulator QH 450 Genetic regulation QH 450-450.6 Genes, Reiterated see Multigene Family Genes, Spliced see DNA, Recombinant Genes, Split see ...

... monogenic epilepsy syndromes (ie epilepsy caused by a mutation in a single gene) are recognised.75 When assessing a patient with epilepsy a comprehensive history with particular focus on the family history should be taken, and an accurate epilepsy ...

... harbor recognizable members of the cellular on~ cogene family. Candidates to date include sre, fps, myc, mos and ras, and the - 6- search is on for others. Once the identity of any of these genes has been vali- dated, targeted mutagenesis and other ...

... human inherited diseases. Human diseases undergoing linkage analysis, gene isolation, ... families with inherited cataracts in preparation for study of ...

... E. coli detecting either forward or back point (gene) mutations (Fahrig, ... activating host and Salmonella typhimurium G46, Serratia marcescens leu” ...