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3 results
  1. NLM Digital Collections - Enrichment strategies for clinical trials to support determination of effectiveness of human .... 
    Publication: Silver Spring, MD : Center for Drug Evaluation and Research, March 2019
    ... 40% to 60% of all melanomas carry this activating mutation. In a study of 49 patients with melanoma, 11 of 16 patients with BRAF V600E mutation who received vemurafenib had a tumor ...
  2. NLM Digital Collections - Management of lung cancer : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), February 2014
    ... raf murine sarcoma viral oncogene homolog B gene (BRAF) mutation and Kirsten rat sarcoma proto-oncogene (KRAS) mutation. ... cell lung cancer with epidermal growth factor receptor activating mutations (January 2012). yy E rlotinib is accepted for ...
  3. NLM Digital Collections - Annual report - National Eye Institute (1982) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... components of prosthetic intraocular lenses are capable of activating the 33 complement of mediating acute inflammatory reactions. ... is studied by examining their production of lymphocyte activating factor. Monoclonal anti- bodies to T cell subsets, ...