166 results

... et al ., 1999 , Gimenez et al ., 2003 ). (a) Antigen-presenting cells Antigen-presenting cells (APCs) are crucial initiators of adaptive immunity. There ...

... of these cells is associated with changes in antigen-presenting cell function in the direction of suppression; this change ... function but also to active migration of other antigen-presenting cells into the skin. A reduction in natural killer ...

... abolished the suppression. I-J + , Thy-1 − , Ia − antigen-presenting cells, which are also resistant to low doses of ... decreases its activity ( Stingl et al. , 1983 ). When antigen-presenting cells are exposed to UVR, their ability to activate ...

... composed of autologous peripheral blood mononuclear cells, including antigen-presenting cells, activated ex vivo with a recombinant fusion protein ... vaccines to their destination in vivo , where the antigen-presenting cells can induce an immune response. Johnson and his ...

... usually be presented to T cells by specialized antigen-presenting cells, of which the dendritic cell subtypes are among ... and below the epithelial cells, per se, are antigen-presenting cells (e.g., dendritic cells) and several intraepithelial leukocytes ( ...

... an antigen, which is exposed to them by antigen-presenting cells. The antigen is a peptide fragment generated by antigen-presenting cells when they degrade the foreign protein. To be ...

... are taken via pinocytosis or endocytosis by the antigen-presenting cells in the skin. These antigen-presenting cells upregulate the expressions of surface molecules and cytokines. ...

... secreted antigen, it is poorly cross-presented by antigen-presenting cells and/or that the local immune environment of ... to draining lymph nodes, they change into potent antigen-presenting cells with enhanced expression of MHC and co-stimulatory ...

... activation occurs by interaction with pro-APCs (“professional” antigen-presenting cells), mainly dendritic cells in lymph nodules/follicles, and ... activation occurs by interaction with pro-APCs (“professional” antigen-presenting cells), mainly dendritic cells in lymph nodules/follicles, which ...

... detection of the virus ( Schrier et al. , 1990 ). Antigen presenting cells such as dendritic and Langerhans' cells may be ... al. , 1993b ). With progression of infection, the FDC-antigen-presenting cell-reticulum is destroyed, probably by immunopathological mechanisms and/ ...