Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

10 results

  1. NLM Digital Collections - Management of early rheumatoid arthritis : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), February 2011
    ... COX-1 and COX-2 in differing ratios. Selective COX- 2 inhibitors or coxibs were designed to avoid gastroduodenal ulceration ... NSAIDs. A health technology assessment 1++ concluded that selective COX-2 inhibitors have a similar efficacy to NSAIDs.51 5. ...
  2. ... Whilst there is clear evidence that the more selective COX-2 inhibitors such as rofecoxib do produce fewer serious GI ... et al. Improvement in gastrointestinal tolerability of the selective cyclooxygenase (COX)-2 inhibitor, meloxicam, compared with piroxicam: results of the Safety ...
  3. NLM Digital Collections - Treatment options for osteoarthritis : scientific review 
    Publication: [Oakland, Calif.] : California HealthCare Foundation, c2004
    ... yet developed appreciable muscle weakness The introduction of selective NSAIDs—COX-2 and wasting or cardiovascular deconditioning are inhibitors (e.g., celecoxib, rofecoxib) and COX-2 the ...
  4. NLM Digital Collections - Management of chronic pain : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), December 2013
    ... upper GI bleeding/perforation is seen with non-selective NSAIDs; those with a long half-life and slow-release preparations. The highest risk is with piroxicam (RR 9.94, 95% CI 5.99 to16.50) followed by naproxen (RR 5.57, 95% CI 3.94 to 7.87) whereas COX-2 inhibitors such as celecoxib (RR 1.42, 95% CI ...
  5. ... Prevention S.D. Solomon and Others Complications of the COX-2 Inhibitors Parecoxib and Valdecoxib after Cardiac Surgery N.A. ... D.l. Rosenthal, and P.M. Arnell EDITORIALS COX-2 Inhibitors — A Lesson in Unexpected Problems J-M. Drazen ...
  6. ... Suppl):S749-52; discussion S753-6 Celecoxib: a COX-2 inhibitor. Andrews SA, et al. Am J Manag Care ... Med Care 1999 May; 37(5):518-25 Cox-2 inhibitors. Brown E. Physician Exec 1999 Jan-Feb;25( ...
  7. ... calcium 7.5 Organizational Effectiveness Results channel blockers, COX-2 inhibitors, antihistamines, and tramadol. = The year- 7.5.a. ...
  8. ... used for calculations.?* ' Assessment of Coronary-Ariery Disease Selective coronary arteriography was performed using previously described techniques. ... The LRC-CPPT was conducted in a highly selective group of 3,806 middle-aged men free ...
  9. ... but it seems probable that molecular targeted imaging, selective drug delivery (therapeutic imaging) and inter- ventional imaging ... ufacturing and imaging. Targeted imaging could allow the selective enhancement of specific structures or tis- sues by ...
  10. NLM Digital Collections - Prevention and management of venous thromboembolism : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), October 2014
    ... 6fondaparinux The synthetic pentasaccharide fondaparinux is a highly selective, indirect inhibitor of factor Xa. It is licensed ... at a therapeutic thrombolysis and/or thrombectomy with selective endovascular dose in patients with renal insufficiency. J ...