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WHIM syndrome 1
- ... CXCR4 PubMed CHEMOKINE, CXC MOTIF, RECEPTOR 4; CXCR4 WHIM SYNDROME 1; WHIMS1 NCBI Gene ClinVar Cao Y, Hunter ZR, ... internalization of carboxy-terminus truncated CXCR4 responsible for WHIM ... CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis. Blood. 2004 ...
- Immune System and Disorders (National Library of Medicine)What is the immune system? Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other ...
- ... S, Rodig S, Castillo JJ, Treon SP. The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia. Leukemia. 2015 Jan;29(1):169-76. doi: 10.1038/leu.2014.187. ...