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Results 1 - 4 of 4 for Desmoid tumor caused by somatic mutation
  1. ... instead, accumulates in cells. Excess beta-catenin, whether caused by CTNNB1 or APC gene mutations, promotes uncontrolled ... gene mutations that occur during a person's lifetime, called somatic mutations. A somatic mutation in one copy of ...
  2. ... uncontrolled proliferation of cells, allowing the formation of desmoid tumors. More About This Health Condition Somatic mutations in the CTNNB1 gene are found in almost ...
  3. ... 10 to 15 percent of non-inherited (sporadic) desmoid tumors; these mutations are somatic, which means they are acquired during a person's lifetime and are present only in tumor cells.Most APC gene mutations that cause sporadic desmoid tumors lead to an abnormally short APC protein. ...
  4. ... Also of particular significance are noncancerous growths called desmoid tumors. These fibrous tumors usually occur in the tissue ... be provoked by surgery to remove the colon. Desmoid tumors tend to recur after they are surgically removed. ...