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Spinal Muscular Atrophy

What is spinal muscular atrophy (SMA)?

Spinal muscular atrophy (SMA) is a group of genetic diseases that damages and kills motor neurons. Motor neurons are a type of nerve cell in the spinal cord and lower part of the brain. They control movement in your arms, legs, face, chest, throat, and tongue.

As the motor neurons die off, your muscles start to weaken and atrophy (waste away). The muscle damage gets worse over time and can affect speaking, walking, swallowing, and breathing.

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Results 1 - 10 of 196 for Spinal muscular atrophy
  1. Spinal Muscular Atrophy (National Library of Medicine)  
    What is spinal muscular atrophy (SMA)? Spinal muscular atrophy (SMA) is a group of genetic diseases that damages and kills motor neurons. Motor neurons are a type of nerve cell in ...
    https://medlineplus.gov/spinalmuscularatrophy.html - Health Topics
  2. Spinal muscular atrophy with lower extremity predominance 
    Spinal muscular atrophy with lower extremity predominance (SMA-LED) is characterized by muscle weakness and wasting (atrophy) in the lower limbs, most severely ...
    https://medlineplus.gov/...atrophy-with-lower-extremity-predominance - Genetics
  3. Spinal muscular atrophy with respiratory distress type 1 
    Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is an inherited condition that causes muscle weakness and respiratory failure typically beginning ...
    https://medlineplus.gov/...-atrophy-with-respiratory-distress-type-1 - Genetics
  4. X-linked infantile spinal muscular atrophy 
    X-linked infantile spinal muscular atrophy is a condition that affects only boys and is characterized by severe muscle weakness and absent reflexes (areflexia). ...
    https://medlineplus.gov/...-linked-infantile-spinal-muscular-atrophy - Genetics
  5. Spinal muscular atrophy with progressive myoclonic epilepsy 
    Spinal muscular atrophy with progressive myoclonic epilepsy (SMA-PME) is a neurological condition that begins in childhood. SMA-PME ... jerks (myoclonic epilepsy).In individuals with SMA-PME, spinal muscular atrophy results from a loss of specialized nerve cells, ...
    https://medlineplus.gov/...rophy-with-progressive-myoclonic-epilepsy - Genetics
  6. Spinal muscular atrophy 
    Spinal muscular atrophy is a genetic disorder characterized by weakness and wasting (atrophy) in muscles used for movement (skeletal ... worsens with age. There are many types of spinal muscular atrophy that are caused by changes in the same ...
    https://medlineplus.gov/genetics/condition/spinal-muscular-atrophy - Genetics
  7. Spinal muscular atrophy 
    Spinal muscular atrophy (SMA) is a group of disorders of the motor neurons (motor cells). These disorders are passed ... Philadelphia, PA: Elsevier; 2022:chap 97. Haliloglu G. Spinal muscular atrophies. In: Kliegman RM, St. Geme JW, Blum NJ, ...
    https://medlineplus.gov/ency/article/000996.htm - Medical Encyclopedia
  8. Spinal Muscular Atrophy From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)  
    Spinal Muscular Atrophy/Start Here ... Spinal Muscular Atrophy ... National Institute of Neurological Disorders and Stroke ... Spinal muscular atrophy (SMA) refers to ...
    https://www.ninds.nih.gov/.../disorders/spinal-muscular-atrophy - External Health Links
  9. Spinal and bulbar muscular atrophy 
    ... 18. Citation on PubMed Finsterer J. Bulbar and spinal muscular atrophy (Kennedy's disease): a review. Eur J Neurol. ... G, Kemp MQ. Androgen receptor and Kennedy disease/spinal bulbar muscular atrophy. Horm Behav. 2008 May;53(5):729-40. ...
    https://medlineplus.gov/.../spinal-and-bulbar-muscular-atrophy - Genetics
  10. Learning about Spinal Muscular Atrophy From the National Institutes of Health (National Human Genome Research Institute)  
    Spinal Muscular Atrophy/Genetics ... Spinal Muscular Atrophy ... National Human Genome Research Institute ... From the National Institutes of Health ... Spinal muscular atrophy ...
    https://www.genome.gov/Genetic-Disorders/Spinal-Muscular-Atrophy - External Health Links
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