Skip navigation

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Results 1 - 10 of 183 for Fusion protein
  1. Core binding factor acute myeloid leukemia 
    ... genes leads to production of the RUNX1-ETO fusion protein. This fusion protein is able to form CBF and attach to ... these genetic rearrangements is called CBFβ-MYH11. The fusion protein can form CBF, but it is thought that ...
    https://medlineplus.gov/...ore-binding-factor-acute-myeloid-leukemia - Genetics
  2. ALK gene 
    ... to the NPM gene and results in a fusion protein called NPM-ALK. In addition, at least seven ... called EML4 and results in the EML4-ALK fusion protein.The fusion proteins created by these rearranged genes ...
    https://medlineplus.gov/genetics/gene/alk - Genetics
  3. PDGFB gene 
    ... PDGFB fusion gene provides instructions for making a fusion protein. In the translocation, the PDGFB gene loses the ... its activity, and production of the COL1A1-PDGFB fusion protein is controlled by COL1A1 gene sequences. As a ...
    https://medlineplus.gov/genetics/gene/pdgfb - Genetics
  4. PDGFRB-associated chronic eosinophilic leukemia 
    ... Like the normal PDGFRβ protein, the ETV6/PDGFRβ fusion protein turns on signaling pathways. However, the fusion protein does not need to be turned on to ...
    https://medlineplus.gov/...-associated-chronic-eosinophilic-leukemia - Genetics
  5. Chromosome 21 
    ... called a somatic mutation, is not inherited.The fusion protein produced from the t(8;21) translocation, called ... gene, turns off gene activity. The RUNX1-ETO fusion protein forms CBF and attaches to DNA, but instead ...
    https://medlineplus.gov/genetics/chromosome/21 - Genetics
  6. Dermatofibrosarcoma protuberans 
    ... gene provides instructions for making an abnormal combined (fusion) protein that researchers believe ultimately functions like the PDGFB ... functions like the PDGFB protein. In excess, this fusion protein stimulates cells to proliferate and differentiate abnormally, leading ...
    https://medlineplus.gov/.../dermatofibrosarcoma-protuberans - Genetics
  7. ETV6 gene 
    ... individual genes. Unlike the normal PDGFRβ protein, the fusion protein is always active, which means certain cell signaling pathways are constantly turned on. The fusion protein is unable to repress gene activity regulated by ...
    https://medlineplus.gov/genetics/gene/etv6 - Genetics
  8. COL1A1 gene 
    ... PDGFB gene provides instructions for making a combined (fusion) protein that researchers believe ultimately functions like the active ... its activity, and production of the COL1A1-PDGFB fusion protein is controlled by COL1A1 gene sequences. As a ...
    https://medlineplus.gov/genetics/gene/col1a1 - Genetics
  9. PDGFRA-associated chronic eosinophilic leukemia 
    ... PDGFRA fusion genes) provides instructions for making a fusion protein that has the function of the normal PDGFRA protein. However, the fusion protein does not require ligand binding to be activated. ...
    https://medlineplus.gov/...-associated-chronic-eosinophilic-leukemia - Genetics
  10. Chromosome 22 
    ... PDGFB gene provides instructions for making a combined (fusion) protein that ultimately functions like the active PDGFB protein. ... its activity, and production of the COL1A1-PDGFB fusion protein is controlled by COL1A1 gene sequences. As a ...
    https://medlineplus.gov/genetics/chromosome/22 - Genetics
previous · 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · next