Results 1 - 6 of 6 for "2-hydroxyglutarate"
  1. ... provides instructions for making an enzyme called L-2-hydroxyglutarate dehydrogenase. This enzyme is found in mitochondria, which ... that produce energy for cell activities. Specifically, L-2-hydroxyglutarate dehydrogenase converts a compound called L-2-hydroxyglutarate ...
  2. ... provides instructions for making an enzyme called D-2-hydroxyglutarate dehydrogenase. This enzyme is found in mitochondria, which ... that produce energy for cell activities. Specifically, D-2-hydroxyglutarate dehydrogenase converts a compound called D-2-hydroxyglutarate ...
  3. ... cells. The enzymes break down compounds called D-2-hydroxyglutarate and L-2-hydroxyglutarate, respectively, as part of a series of reactions ... a shortage of functional enzyme, which allows D-2-hydroxyglutarate or L-2-hydroxyglutarate to build up in ...
  4. ... function: the production of a compound called D-2-hydroxyglutarate. Because the genetic changes lead to an enzyme ... people with D-2-HGA type II, D-2-hydroxyglutarate builds up abnormally in cells. At high levels, ...
  5. ... function: the production of a compound called D-2-hydroxyglutarate. Because the genetic changes lead to an enzyme ... mutations that result in the production of D-2-hydroxyglutarate. Studies suggest that an increase in D-2- ...
  6. ... up abnormally within cells. These compounds include D-2-hydroxyglutarate and L-2-hydroxyglutarate, which at high levels can damage cells and ...