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Sickle Cell Disease

What is sickle cell disease (SCD)?

Sickle cell disease (SCD) is a group of inherited red blood cell disorders. If you have SCD, there is a problem with your hemoglobin. Hemoglobin is a protein in red blood cells that carries oxygen throughout the body. With SCD, the hemoglobin forms into stiff rods within the red blood cells. This changes the shape of the red blood cells. The cells are supposed to be disc-shaped, but this changes them into a crescent, or sickle, shape.

The sickle-shaped cells are not flexible and cannot change shape easily. Many of them burst apart as they move through your blood vessels. The sickle cells usually only last 10 to 20 days, instead of the normal 90 to 120 days. Your body may have trouble making enough new cells to replace the ones that you lost. Because of this, you may not have enough red blood cells. This is a condition called anemia, and it can make you feel tired.

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Results 1 - 10 of 349 for sickle cell anemia
  1. Sickle Cell Disease (National Library of Medicine)  
    What is sickle cell disease (SCD)? Sickle cell disease (SCD) is a group of inherited red blood cell disorders. If you have SCD, there is a problem with ...
  2. ... following organizations are good resources for information on sickle cell anemia : American Sickle Cell Anemia Association -- ascaa.org Centers ...
  3. Sickle cell disease is a disorder passed down through families. The red blood cells that are normally shaped like ... Sickle cell disease is caused by an abnormal type of hemoglobin called hemoglobin S. Hemoglobin is a protein inside red ...
  4. ... in hemoglobin is replaced with hemoglobin S. In sickle cell anemia (also called homozygous sickle cell disease or HbSS ... hemoglobin S Genetic Testing Registry: Hb SS disease Sickle cell anemia National Organization for Rare Disorders (NORD) ClinicalTrials.gov ...
  5. ... children 2 years of age and older with sickle cell anemia (an inherited blood disorder in which the red ... of cancer cells in your body. Hydroxyurea treats sickle cell anemia by helping to prevent formation of sickle-shaped ...
  6. Sickle Cell Disease Association of America (Sickle Cell Disease Association of America)  
    ... Cell and Gene Therapy Access Model,... Read more Sickle Cell Disease is Not a Joke This weekend’s Saturday Night ... recently completed a... Read more NFL players spotlight Sickle Cell Disease Association of America The NFL’s My Cause My ...
  7. Sickle Cell Disease (For Teens) Video (Nemours Foundation)  
  8. ... children 5 years of age and older with sickle cell anemia (an inherited blood disorder in which the red blood cells are abnormally shaped [shaped like a sickle] and cannot bring enough oxygen to all parts ...
  9. ClinicalTrials.gov: Anemia, Sickle Cell From the National Institutes of Health (National Institutes of Health)  
    Sickle Cell Disease/Clinical Trials ... Sickle Cell Disease
  10. About Sickle Cell Disease From the National Institutes of Health (National Human Genome Research Institute)  
    Sickle Cell Disease/Genetics ... Sickle Cell Disease ... National Human Genome Research Institute ... From the National Institutes of Health ... Sickle cell disease is a ...
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