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2,407 results

  1. NLM Digital Collections - Nonclinical evaluation of the immunotoxic potential of pharmaceuticals : guidance for industry 
    Publication: Silver Spring, MD : Center for Drug Evaluation and Research, June 2023
    resource.nlm.nih.gov/9918662583506676
    ... Assessment of the risks associated with a heightened immune response normally requires a safety evaluation paradigm that differs ... stopping criteria. For biopharmaceuticals intended to stimulate an immune response either directly or indirectly, a starting dose based ...
  2. NLM Digital Collections - SUMEX grant proposal 
    Publication: Produced: 1972
    resource.nlm.nih.gov/101584906X16936
    ... in the humoral (antibody) and cell mediated (hypersensitivity) immune response. Antigen binding cells, thymus derived cells, bone-marrow ... on Thymus and Bone Marrow Cells in the Immune Response, Annual Meeting of the American Society for Hematology, ...
  3. NLM Digital Collections - Hospital literature index (Volume 40) 
    resource.nlm.nih.gov/7807587X27
    ... Res] 1984 Mar 31; 288(6422):988-91 Immune response to hepatitis B vaccine in staff and patients ... Distrib 1984 Mar-Apr; 2(2):56-62 Immune response to hepatitis B vaccine in staff and patients ...
  4. NLM Digital Collections - Use of International Standard ISO 10993-1, "Biological evaluation of medical devices - Part 1:... 
    Publication: Silver Spring, MD : Center for Devices and Radiological Health, September 8, 2023
    resource.nlm.nih.gov/9918716788306676
    ... irritation, · sensitization (delayed Type IV hypersensitivity), · allergy, and · immune response or other reactions on the skin where the ... e.g., redness (erythema), swelling (edema), allergy, and immune response or other reactions on the skin where the ...
  5. NLM Digital Collections - Presidential Commission on the HIV Epidemic, hearing on Response to the Pandemic by the ... 
    Publication: Produced: 19 April 1988
    resource.nlm.nih.gov/101763264X120
    ... 1987. The findings have worldwide significance since inadequate immune response to vaccine antigens in these children could affect ... investigators to determine which aspects of the host immune response are important in the response to EBY. AIDS ...
  6. NLM Digital Collections - Human Cytomegalovirus Infection and Disease (Osborn, J.), 1980 
    https://resource.nlm.nih.gov/101647507X393
    ... regulatory cells may mediate the acute perturbations in immune response. It would be helpful to know if a ... nors. Newer techniques for the measurement of humoral immune response include im- munoperoxidase and enzyme-linked-im- munoabsorbent ( ...
  7. NLM Digital Collections - British guideline on the management of asthma : a national clinical guideline 
    Publication: Edinburgh, Scotland : Scottish Intercollegiate Guidelines Network (SIGN), September 2016
    resource.nlm.nih.gov/101714879
    ... allergen, as a means to switch off allergic immune responses. There are some observations suggesting that benefit might ... life in 1++ children with asthma.375 The immune response to the immunisation may be adversely affected by ...
  8. NLM Digital Collections - Human Cytomegalovirus Infection and Disease (Osborn, J.), 1986 
    https://resource.nlm.nih.gov/101647507X399
    ... cells may mediate the acute perturba- tions in immune response. It would be helpful to know if a ... Newer techniques for the measure- ment of humoral immune response include immunoperoxidase and enzyme- linked-immunoabsorbent (ELISA) as- ...
  9. NLM Digital Collections - Rare diseases. Although limited, available evidence suggests medical and other costs can be ... 
    Publication: Washington, DC : United States Government Accountability Office, October 2021
    resource.nlm.nih.gov/9918383083506676
    ... deficiency diseases are genetic disorders that impair the immune response. As a result, people with these diseases may ... deficiency diseases are genetic disorders that impair the immune response. As a result, people with these diseases may ...
  10. NLM Digital Collections - Dupilumab and crisaborole for atopic dermatitis : effectiveness and value : final evidence ... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, June 8, 2017
    resource.nlm.nih.gov/101723893
    ... alters type 2 helper T (Th2) cell mediated immune responses and improves epidermal barrier abnormalities in atopic dermatitis. ... with a novel mechanism of action affecting the immune response, and we lack adequate long-term safety data. ...
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