- NLM Digital Collections - Annual report - National Eye Institute (1993)Publication: [Bethesda, Md.] : National Eye Institute... better understanding of the physiological regulation of the ornithine 5-aminotransferase (OAT) and its regulation in vivo. ... FY 1993 Laboratory of Immunology Project Description Objectives Ornithine 5-aminotransferase (OAT, L-omithine:2- oxoacid aminotransferase, ...
- NLM Digital Collections - Annual report - National Eye Institute (1978)Publication: [Bethesda, Md.] : National Eye Institute... trans- formed in tissue culture, and assayed for ornithine aminotransferase activity. Skin fibroblasts grown in tissue culture are assayed for ornithine aminotrans- ferase. Other enzjnnatic activities related to ornithine ...
- NLM Digital Collections - Annual report - National Eye Institute (1979)Publication: [Bethesda, Md.] : National Eye Institute... that their transformed lymphocytes have a deficiency of ornithine aminotransferase. The demonstration of this metabolic defect suggested ... by dietary restriction of arginine, the precursor of ornithine, and by supplementation of the diet with pyridoxine, ...
- NLM Digital Collections - Annual report - National Eye Institute (1994)Publication: [Bethesda, Md.] : National Eye Institute... 149 Retinal Survival in Transgenic Mice Expressing Human Ornithine 6-Aminotransferase 152 Enzymatic Correction of OAT Deficiency: ... natural histo- ry and the role of the ornithine aminotiansfer- ase gene in the development of gyrate ...
- NLM Digital Collections - Annual report - National Eye Institute (1992)Publication: [Bethesda, Md.] : National Eye Institute... be many different single-point mutations in the ornithine aminotransfer- ase gene in gyrate atrophy patients. Dietary ... centered on the development of a construct of ornithine aminotrans- ferase that can be used for gene ...
- NLM Digital Collections - Annual report - National Eye Institute (1982)Publication: [Bethesda, Md.] : National Eye Institute... members grown in tissue culture are assayed for ornithine amino-6- transf erase activity. The results will ... of pyridoxine to see if serum concentration of ornithine can be reduced, and if so, the patient ...
- NLM Digital Collections - Annual report - National Eye Institute (1984)Publication: [Bethesda, Md.] : National Eye Institute... are grown in tissue culture and assayed for ornithine aminotransferase act i vi ty . The results will ... of pyridoxine to see if serum concentration of ornithine can be reduced, and, if so, the patient ...
- NLM Digital Collections - Annual report - National Eye Institute (1985)Publication: [Bethesda, Md.] : National Eye Institute... is caused by a deficiency of the enzyme ornithine aminotransferase (OAT) which results in a hyperornithinia in ... shown that diets which restrict the sources of ornithine seem to protect and even improve visual function. ...
- NLM Digital Collections - Science as a Way of Knowing III - GeneticsPublication: Produced: December 1985... arginine is formed from citrulline, citrul- line from ornithine, and ornithine from an unknown precursor. A specific enzyme is ... the seven would grow if either citrulline or ornithine was used to replace arginine. Your students should ...
- NLM Digital Collections - Effects of Colicins E1 and K on Cellular MetabolismPublication: American Society for Microbiology, January 1969... acids, proteins and polysaccharides, and the conversion of ornithine to citrulline. Respiration was only partially affected, and ... as are other energy-requiring reactions. Conversion of ornithine to citrulline. Con- ceivably, the interference of colicins ...