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66 results

  1. NLM Digital Collections - Annual report - National Eye Institute (1993) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... better understanding of the physiological regulation of the ornithine 5-aminotransferase (OAT) and its regulation in vivo. ... FY 1993 Laboratory of Immunology Project Description Objectives Ornithine 5-aminotransferase (OAT, L-omithine:2- oxoacid aminotransferase, ...
  2. NLM Digital Collections - Annual report - National Eye Institute (1978) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... trans- formed in tissue culture, and assayed for ornithine aminotransferase activity. Skin fibroblasts grown in tissue culture are assayed for ornithine aminotrans- ferase. Other enzjnnatic activities related to ornithine ...
  3. NLM Digital Collections - Annual report - National Eye Institute (1979) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... that their transformed lymphocytes have a deficiency of ornithine aminotransferase. The demonstration of this metabolic defect suggested ... by dietary restriction of arginine, the precursor of ornithine, and by supplementation of the diet with pyridoxine, ...
  4. NLM Digital Collections - Annual report - National Eye Institute (1994) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... 149 Retinal Survival in Transgenic Mice Expressing Human Ornithine 6-Aminotransferase 152 Enzymatic Correction of OAT Deficiency: ... natural histo- ry and the role of the ornithine aminotiansfer- ase gene in the development of gyrate ...
  5. NLM Digital Collections - Annual report - National Eye Institute (1992) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... be many different single-point mutations in the ornithine aminotransfer- ase gene in gyrate atrophy patients. Dietary ... centered on the development of a construct of ornithine aminotrans- ferase that can be used for gene ...
  6. NLM Digital Collections - Annual report - National Eye Institute (1982) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... members grown in tissue culture are assayed for ornithine amino-6- transf erase activity. The results will ... of pyridoxine to see if serum concentration of ornithine can be reduced, and if so, the patient ...
  7. NLM Digital Collections - Annual report - National Eye Institute (1984) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... are grown in tissue culture and assayed for ornithine aminotransferase act i vi ty . The results will ... of pyridoxine to see if serum concentration of ornithine can be reduced, and, if so, the patient ...
  8. NLM Digital Collections - Annual report - National Eye Institute (1985) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... is caused by a deficiency of the enzyme ornithine aminotransferase (OAT) which results in a hyperornithinia in ... shown that diets which restrict the sources of ornithine seem to protect and even improve visual function. ...
  9. ... arginine is formed from citrulline, citrul- line from ornithine, and ornithine from an unknown precursor. A specific enzyme is ... the seven would grow if either citrulline or ornithine was used to replace arginine. Your students should ...
  10. NLM Digital Collections - Effects of Colicins E1 and K on Cellular Metabolism 
    Publication: American Society for Microbiology, January 1969
    ... acids, proteins and polysaccharides, and the conversion of ornithine to citrulline. Respiration was only partially affected, and ... as are other energy-requiring reactions. Conversion of ornithine to citrulline. Con- ceivably, the interference of colicins ...
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