Klippel-Feil syndrome is a bone disorder characterized by the abnormal joining (fusion) of two or more spinal bones in the neck (cervical vertebrae). The vertebral fusion is ...

... 2 or the Langer-Saldino type. This rare disorder of bone development is characterized by short arms and legs, ... have been found to cause hypochondrogenesis, a severe disorder of bone growth characterized by a small body, short limbs, ...

... disease, also called infantile cortical hyperostosis, is a bone disorder that most often occurs in babies. Excessive new bone formation (hyperostosis) is characteristic of Caffey disease. The ...

Tarsal-carpal coalition syndrome is a rare, inherited bone disorder that affects primarily the hands and feet. Several individual bones make up each wrist (carpal bones) and ankle ( ...

Melorheostosis is a rare bone disease. It causes the abnormal growth of new bone tissue on the surface of existing bones. The new bone has a ... RAS/MAPK signaling pathway, may also cause the disorder. MAP2K1 ... from somatic mutations in bone cells that occur during an individual's lifetime. ...

Legg-Calvé-Perthes disease is a bone disorder that affects the hips. Usually, only one hip is involved, but in about 10 percent of cases, both hips are affected. Legg- ...

Pyle disease is a disorder of the bones. Its hallmark feature is an abnormality of the long bones in the arms and legs in which the ends (metaphyses) ... they may have mild abnormalities of the long bones. Metaphyseal dysplasia, Pyle type Pyle metaphyseal dysplasia Pyle's disease Pyle's ... PYLE DISEASE; PYL PubMed Galada ...

... brain that are found in people with this disorder.The bone abnormalities associated with PLOSL usually become apparent in ... the bone changes seen in people with this disorder are related to ... to resorb bone tissue during bone remodeling. In the central nervous ...