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Progressive peripheral neuropathy
- ... hereditary spastic paraplegias. These disorders are characterized by progressive muscle stiffness (spasticity) and the development of paralysis ... and brain, spastic paraplegia type 15 affects the peripheral nervous system, ... (sensory neuropathy); impairment of the nerves used for muscle movement ( ...
- ... Features that appear later in life can include progressive muscle weakness and wasting; poor balance and coordination ( ...