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Results 11 - 20 of 28 for Severe "T-cell" immunodeficiency
  1. ... reduced numbers of these cells. A shortage of T cells impairs the immune response to foreign invaders, accounting for the severe skin infections common in DOCK8 immunodeficiency syndrome. A lack of DOCK8 protein also impairs ...
  2. ... links caspase recruitment domain 11 (CARD11) inactivation to severe combined ... alterations in adult T-cell leukemia/lymphoma. Cancer Sci. 2017 Sep;108(9): ...
  3. ... the IL7R gene can cause a form of severe combined immunodeficiency (SCID), in which affected individuals have decreased immune function and are prone to recurrent and persistent infections. Affected individuals with IL7R gene mutations have few or no T cells but normal numbers of B cells and another ...
  4. The FOXN1 gene provides instructions for making a protein that attaches (binds) to specific regions of DNA and regulates the activity of other genes. On the ...
  5. ... of another type of lymphocyte called B cells. T cells, B cells, and natural killer cells attack bacteria, ... severe combined immunodeficiency (SCID), an impairment of the immune system that ...
  6. ... Omenn syndrome leads to immature self-reactive oligoclonal T cells. J Allergy Clin ... severe combined immunodeficiency. J Allergy Clin Immunol. 2008 Dec;122(6): ...
  7. ... cell development and function. It is thought that T cells and NK cells ... in DOCK8 immunodeficiency syndrome. A lack of DOCK8 protein also impairs ...
  8. ... 14 Immunodeficiency 36 P110δ-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency PASLI Genetic Testing Registry: Immunodeficiency 36 with lymphoproliferation ...
  9. ... Casanova JL. Human IkappaBalpha Gain of Function: a Severe and Syndromic Immunodeficiency. J Clin Immunol. 2017 Jul;37(5):397- ...
  10. ... can lead to virus reactivation. Infection with human immunodeficiency virus (HIV), which infects and kills T cells, can also allow the virus to become active ...
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