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Progressive peripheral neuropathy
- Leg Injuries and Disorders (National Library of Medicine)Your legs are made up of bones, blood vessels, muscles, and other connective tissue. They are important for motion and standing. Playing sports, running, ...
- ... disorder include numbness and tingling in the legs (peripheral neuropathy) and progressive muscle weakness and stiffness (spasticity). As a result, ...
- ... the brain and spine. These are called the peripheral nerves.
- ... tremor/ataxia syndrome (FXTAS). FXTAS is characterized by progressive problems with movement (ataxia), tremor, memory loss, reduced sensation in the lower extremities (peripheral neuropathy), and mental and behavioral changes. The disorder usually ...
- ... or orthostatic hypertension. These abnormalities can lead to progressive heart failure and death. Occasionally, people with the cardiac form of transthyretin amyloidosis have mild peripheral neuropathy. A less common form of transthyretin amyloidosis, called ...
- ... They do, however, have a significant risk of progressive neurological problems such as tremors, difficulty with movement and balance (ataxia), reduced sensation and weakness in the arms and legs (peripheral neuropathy), and a decline in intellectual functioning. Chediak-Higashi ...
- Fragile X Syndrome/Start Here ... Fragile X Syndrome ... National Human Genome Research Institute ... From the National Institutes of Health ... Fragile X syndrome is an ...
- ... teeth, and a small lower jaw.CCFDN causes progressive damage to the peripheral nerves, which connect the brain and spinal cord to muscles and sensory cells. This nerve damage is known as peripheral neuropathy. Weakness in the legs, followed by the arms, ...
- ... people with metachromatic leukodystrophy, white matter damage causes progressive ... incontinence, seizures, paralysis, an inability to speak, blindness, ...
- ... with spastic paraplegia type 3A can also experience progressive muscle wasting (amyotrophy) in the lower limbs, reduced bladder control, an abnormal curvature of the spine (scoliosis), loss of sensation in the feet (peripheral neuropathy), or high arches of the feet (pes cavus). ...