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225 results
  1. ... in 175 patients.[ 10 ] Ibrutinib is a selective irreversible inhibitor of Bruton's tyrosine kinase, a signaling molecule ... obinutuzumab.[ 19 ] Acalabrutinib is a highly selective covalent irreversible Bruton tyrosine kinase inhibitor, designed to minimize the gastrointestinal toxicities and risk ...
  2. ... ACID 2,4,5-TRICHLOROPHENOXYACETIC ACID CHOLINESTERASE INHIBITORS, IRREVERSIBLE CHOLINESTERASE INHIBITORS, REVERSIBLE ADRENERGIC ALPHA RECEPTOR BLOCKADERS ADRENERGIC BETA RECEPTOR ...
  3. NLM Digital Collections - Annual report - National Eye Institute (1993) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... T, Itabe H, Kador PF, Miller DD: Selective irreversible inhibitors of aldose reductase. J Med Chem 35:1117- ...
  4. NLM Digital Collections - Review of intramural research (1961) 
    Publication: [Bethesda, Md.] : U.S. Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health
    ... chains would be more effective and per- haps irreversible inhibitors of the enzymes : -NH2 phenylethylamine (substrate) H E — ...
  5. NLM Digital Collections - Annual report - National Eye Institute (1994) 
    Publication: [Bethesda, Md.] : National Eye Institute
    ... 2 ceUs. (3) MDL 28,842, a potent irreversible inhibitor of S-adenosyl-L-homocysteine hydro- lase was shown ...
  6. ... myocardial 1+ revascularisation.131,132 Aspirin is an irreversible inhibitor of cyclo-oxygenase, which platelets (unlike vascular endothelium) ...
  7. ... 6% vs. 0.2%). Neratinib Neratinib is an irreversible tyrosine kinase inhibitor of HER1, HER2, and HER4, which has been ...
  8. NLM Digital Collections - Symposium on Military Physiology : under the auspices of the Military Establishment Research .... 
    Publication: Washington, D.C. : Military Establishment Research and Development Board, Committee on Geographical Exploration, Panel on Physiology, [1947?]
    ... new type of drugs to the pharmacological armamentarium - irreversible cholinesterase inhibitors lacking any independent pharmacological ac- tion. This is ...
  9. ... NSAIDs) and has been determined to be an irreversible cyclo-oxygenase (COX)-1 and -2 enzyme inhibitor, although unlike other NSAIDs, it affects more of ...
  10. NLM Digital Collections - Vesicular monoamine transporter 2 inhibitors for tardive dyskinesia : effectiveness and value ... 
    Publication: [Boston, Massachusetts] : Institute for Clinical and Economic Review, December 22, 2017
    ... potentially important advancement for individuals with this frequently irreversible condition. In particular, for individuals with severe disabling TD, the use of VMAT2 inhibitors may decrease caregiver/family burden. ©Institute for Clinical ...
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