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2,914 results
  1. ... methods, action and uses, toxicity, methods of administration, dosage forms and literature references. The English edition in Spanish (Medica- mentos de ...
  2. NLM Digital Collections - Cover letter attachments for controlled correspondence and ANDA submissions : guidance for ... 
    Publication: Silver Spring, MD : Center for Drug Evaluation and Research, June 2023
    ... e.g., Original, Amendment) Proposed Product Established Name Dosage Form Strength(s) Reference Listed Drug (RLD) (proprietary name (brand name), application ...
  3. NLM Digital Collections - Questions and answers on biosimilar development and the BPCI Act 
    Publication: Silver Spring, MD : Center for Drug Evaluation and Research, September 2021
    ... that its proposed biosimilar product has the same dosage form as the reference product? .......................... 17 Q.I.19. If a non- ... that its proposed biosimilar product has the same dosage form as the reference product? [Final December 2018] A.I.18. Under ...
  4. NLM Digital Collections - COVID-19 container closure system and component changes : glass vials and stoppers 
    Publication: [Silver Spring, MD] : Center for Drug Evaluation and Research, March 2021
    ... documents specific to various application types and product dosage forms (see section VII., References). The content in section IV., Common Changes Related ...
  5. NLM Digital Collections - Manufacturing, supply chain, and drug and biological product inspections during COVID-19 ... 
    Publication: [Silver Spring, MD] : Center for Drug Evaluation and Research, May 17, 2021
    ... up and postapproval change guidance documents for specific dosage forms (see section V. References). Should circumstances resulting from the COVID-19 pandemic ...
  6. NLM Digital Collections - E6(R2) good clinical practice : integrated addendum to ICH E6(R1) 
    Publication: Silver Spring, MD : Center for Drug Evaluation and Research, March 2018
    ... absolute, where possible, and/or relative) using a reference dosage form. - Population subgroups (e.g., gender, age, and impaired ...
  7. ... 3 MED Dosage Form ID 4 MED Routed Dosage Form Medication Description 5 MED Medication Status Code File: RMIGECD1_REF_GEN_THERAP_DESC MED Reference Generic Therapeutic Equivalence Code Description Table Relates the ...
  8. ... have the same active ingredient, route of administration, dosage form, strength, and proposed labeling as the reference-listed (brand name) drug. The generic drug manufacturer ...
  9. NLM Digital Collections - Generic drug development : stakeholders’ views of risk evaluation and mitigation strategies ... 
    Publication: Washington, DC : United States Government Accountability Office, October 2019
    ... active ingredient(s), conditions of use, route of administration, dosage form, strength, and labeling (with certain permissible differences) and (2) bioequivalent to the reference listed drug, meaning it generally delivers the same ...
  10. NLM Digital Collections - Chemistry, manufacturing, and control (CMC) information for human gene therapy ... 
    Publication: Silver Spring, MD : Center for Biologics Evaluation and Research, January 2020
    ... includes a list of all components of the dosage form, their amounts on a per-batch basis, and a reference to their quality standards. c. Description of Manufacturing ...
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