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Disorder of manganese transport
- ... how its impairment is involved in Hailey-Hailey disease.Although ATP2C1 gene mutations probably also affect the transport of manganese within cells, abnormal manganese regulation is not thought ...
- ... cells (polycythemia); and liver abnormalities, including irreversible liver disease (cirrhosis).Mutations in the SLC30A10 gene impair the transport of manganese out of the cell, allowing the element to ...
- ... These genes provide instructions for making proteins that transport manganese across cell membranes. Manganese is important for many ... of waste material. The SLC30A10 protein may also transport manganese out of brain cells to protect them from ...
- Parkinson's Disease (National Institute of Neurological Disorders and Stroke)Parkinson's disease is a progressive movement disorder of the nervous system. It causes nerve cells (neurons) in parts of the brain to weaken, become damaged, ...