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Results 1 - 7 of 7 for Decreased activity of the pyruvate dehydrogenase complex
  1. PDHA1 gene 
    ... decrease in functional E1 alpha results in reduced pyruvate dehydrogenase complex activity. With decreased function of this complex, pyruvate builds up and ...
    https://medlineplus.gov/genetics/gene/pdha1 - Genetics
  2. PDHB gene 
    ... functional E1 beta leads to a reduction of pyruvate dehydrogenase complex activity. With decreased function of this complex, pyruvate builds up and is converted, in another chemical ...
    https://medlineplus.gov/genetics/gene/pdhb - Genetics
  3. Pyruvate dehydrogenase deficiency 
    ... these other genes lead to a reduction of pyruvate dehydrogenase complex activity.With decreased function of this complex, pyruvate builds up and is converted in another chemical ...
    https://medlineplus.gov/.../pyruvate-dehydrogenase-deficiency - Genetics
  4. DLAT gene 
    ... abnormal E2 enzyme and reduced activity of the pyruvate dehydrogenase complex, although the mechanism is unclear. With decreased activity of this complex, pyruvate builds up and is ...
    https://medlineplus.gov/genetics/gene/dlat - Genetics
  5. PDP1 gene 
    ... cannot remove the phosphate group from the pyruvate dehydrogenase complex, which reduces the activity of the complex. With decreased activity of this complex, pyruvate builds up and is converted, in another chemical ...
    https://medlineplus.gov/genetics/gene/pdp1 - Genetics
  6. PDHX gene 
    ... the binding of the E3 enzyme to the pyruvate dehydrogenase complex, which leads to a reduction of the complex's activity. With decreased function of this complex, pyruvate builds up and ...
    https://medlineplus.gov/genetics/gene/pdhx - Genetics
  7. Leigh syndrome 
    ... caused by variants in genes that form the pyruvate dehydrogenase complex or coenzyme Q10, both of which are involved ...
    https://medlineplus.gov/genetics/condition/leigh-syndrome - Genetics