... to injury. The protein produced from the F2 gene, prothrombin (also called ... mutation that causes prothrombin thrombophilia results in an overactive ...

... formation of blood clots in response to injury. Prothrombin is the precursor ... F2 gene mutations reduce the production of prothrombin in cells, which ...

... the primary protein that makes up blood clots. Thrombin is also thought to be ... 50 mutations in the F2 gene have been found to cause prothrombin deficiency. Most ...

... in conversion of an important coagulation protein called prothrombin to its active form, ... 250 mutations in the F11 gene have been found to cause a rare bleeding ...

... factors to convert an important coagulation protein called prothrombin to its active form, ... least 130 mutations in the F10 gene have been found to cause a rare bleeding ...

... Hoek B, Rosendaal FR. Factor V Leiden mutation, prothrombin gene mutation, and deficiencies in coagulation inhibitors associated with Budd- ...

... published></gene-summary><gene-summary ><gene-symbol >F2</gene-symbol><name >coagulation factor II, thrombin</name><ghr-page >https://medlineplus.gov/genetics/gene/ ...

... genetics/gene/f13b</url></topic><topic ><title >F2: coagulation factor II, thrombin</title><url >https://medlineplus.gov/genetics/gene/f2</url></topic><topic ><title >F5: coagulation factor ...

... inactive) until it attaches to a protein called thrombin, which converts it to ... 270 mutations in the PROC gene have been found to cause protein C deficiency. ...