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  1. Pharmacological interventions - Challenging Behaviour and Learning Disabilities - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK355379
    ... of weight gain and increased the risk of clinically significant weight gain when compared with placebo at the end of ...
  2. Prader-Willi Syndrome - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK1330
    ... if obese or beginning in adolescence or w/rapid significant weight gain or other symptoms (e.g., polyuria/polydipsia) Free ...
  3. Faltering growth after the early days of life - Faltering Growth – recognition and management - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK536441
    ... Olsen 2007 looked at the ability of seven clinically used criteria for ‘moderate’ failure to thrive to identify significant undernutrition defined as the combination of slow conditional weight gain and low BMI: body mass index < 9 th ...
  4. NLM Digital Collections - Be Studies, Reports, Articles, 1959; 1966-1968 
    https://resource.nlm.nih.gov/101084435X86
    ... seven postexposure days. They soon began a normal weight gain and remained clinically healthy until the time of necropsy. No significant gross lesions were observed during a detailed gross ...
  5. NLM Digital Collections - Reducing Tobacco Use: A Report of the Surgeon General 
    Publication: United States. Public Health Service. Office of the Surgeon General, 2000
    resource.nlm.nih.gov/101584932X181
    ... scale might be used as a process measure. Clinically significant outcome measures in- clude attempts at quitting and abstinence success. Withdrawal symptom severity and concomitants of cessation attempts, such as weight gain, may be viewed as outcomes as well. Some ...
  6. NLM Digital Collections - Reducing Tobacco Use: A Report of the Surgeon General (pages 78-102) 
    Publication: United States. Public Health Service. Office of the Surgeon General, 2000
    resource.nlm.nih.gov/101584932X186
    ... scale might be used as a process measure. Clinically significant outcome measures in- clude attempts at quitting and abstinence success. Withdrawal symptom severity and concomitants of cessation attempts, such as weight gain, may be viewed as outcomes as well. Some ...
  7. NLM Digital Collections - Penicillin 
    Publication: [Washington] : United States Office of War Information, 1944
    resource.nlm.nih.gov/10020450R
    ... 30 Kg. A loss of 10 Kg. is clinically obvious. Muscle atrophy and loss of strength precede weight loss, and restoration of muscle bulk and strength appear prior to significant weight gain during convalescence. The distribution of extracellular body fluids ...
  8. NLM Digital Collections - The Health Benefits of Smoking Cessation: A Report of the Surgeon General 
    Publication: United States. Office on Smoking and Health, 1990
    resource.nlm.nih.gov/101584932X37
    ... 6) decreased heart rate (7) increased appetite or weight gain SOURCE: Condensed from the American Psychiatric Association (1987). The signs and symptoms of nicotine withdrawal are observable; they are often of clinically significant magnitude and occur in self-quitters as well ...
  9. NLM Digital Collections - The Health Benefits of Smoking Cessation: A Report of the Surgeon General (pages 501-525) 
    Publication: United States. Office on Smoking and Health, 1990
    resource.nlm.nih.gov/101584932X59
    ... 6) decreased heart rate (7) increased appetite or weight gain SOURCE: Condensed from the American Psychiatric Association (1987). The signs and symptoms of nicotine withdrawal are observable; they are often of clinically significant magnitude and occur in self-quitters as well ...
  10. NLM Digital Collections - Management of obstructive sleep apnoea/hypopnoea syndrome in adults : a national clinical ... 
    Publication: Edinburgh, Scotland : SIGN, c2003
    resource.nlm.nih.gov/101206778
    ... with specific associated symptoms may be suffering from significant underlying ... 2 DEFINITIONS AND BACKGROUND þ Patients suspected ...
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