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Cardiac polyglucosan accumulation
- ... neurons) appear to be particularly vulnerable to the accumulation of polyglucosan bodies in people with this disorder, leading to ...
- ... in cells, leading to damage and cell death. Polyglucosan bodies accumulate in cells throughout the body, but liver cells and muscle cells are most severely affected in GSD IV. Glycogen accumulation in the liver leads to hepatomegaly and interferes ...
