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  1. ... on ribociclib and 7% on placebo). First-line abemaciclib and endocrine therapy Abemaciclib, another CDK4/6 inhibitor, ... endocrine therapy above for more information.) Second-line abemaciclib and endocrine therapy Evidence: The MONARCH 2 ( NCT02107703 ) ...
  2. ... other parts of the body or has recurred. Abemaciclib is a cyclin-dependent kinase inhibitor used to ... Sometimes cyclin-dependent kinase inhibitor therapy ( palbociclib , ribociclib, abemaciclib, or alpelisib) is also given. In premenopausal women ...