... simultaneously with LV) were compared with the same 5-FU/LV regimen without oxaliplatin when administered for 6 months. Each ... analyzed the activity and toxic effects of various 5-FU/LV regimens using different doses and administration schedules and showed ...

... LV/5-FU) were compared with the same 5-FU/LV regimen without oxaliplatin administered for 6 months.[ 26 ] Based ... analyzed the activity and toxic effects of various 5-FU/LV regimens using different doses and administration schedules and showed ...

... is mirrored by the PSA where again the 5-FU based regimens are rarely cost effective. The costs of gemcitabine are also now likely to be much reduced compared to those considered in TA25 ... The costs of gemcitabine and 5-FU are now likely to be very similar and ...

... platinum or platinum/taxane based regimens than with fluorouracil/anthracycline regimens, at the cost of greater treatment toxicity. Rationale ... platinum or platinum/taxane based regimens than with fluorouracil/anthracycline regimens (see Figures Table 23.2 and Table 23. ...

... or capecitabine combined with oxaliplatin and nivolumab. Triplet regimens. 5-FU combined with either epirubicin and cisplatin, etoposide and ... and capecitabine are often substituted for cisplatin and 5-FU within the ECF regimen on the basis of results from the REAL- ...

... 3/4 toxicities: Stomatitis H.17.6. Combination 5-FU (FSM) versus other chemotherapy regimens in adults with locally advanced or metastatic pancreatic ...

... or metastatic pancreatic cancer, compared first-line combination 5-FU with other chemotherapy regimens ( Bukowski et al. 1983 ; Oster et al. 1986 ). ... Table 204 Summary clinical evidence profile for combination 5-FU (FSM) ... chemotherapy regimens in adults with locally advanced or metastatic pancreatic ...

... CP), and epirubicin in combination with cisplatin and fluorouracil (ECF). These regimens were selected after reviewing the available published literature ...

... were randomly assigned to receive pembrolizumab or a 5-FU–containing regimen. The trial showed that pembrolizumab was superior to ... Lakomy R, et al.: Addition of aflibercept to fluorouracil, leucovorin, and ... an oxaliplatin-based regimen. J Clin Oncol 30 (28): 3499-506, 2012. [ ...

... the first-line treatment of metastatic pancreatic cancer. 5-FU, leucovorin, and oxaliplatin (OFF regimen) versus best supportive care (BSC): Second-line chemotherapy ...