... Search term GeneReviews Advanced Search Help < Prev Next > Proteus Syndrome Leslie G Biesecker , MD and Julie C Sapp , ... Testing and Preimplantation Genetic Testing Family history of Proteus syndrome or AKT1 -related overgrowth spectrum. As PS and ...

... glans penis [ Gorlin et al 1992 ]. PTEN -Related Proteus Syndrome PTEN -related Proteus syndrome (PS) is highly variable ... polyps seen in Peutz-Jeghers syndrome . PTEN -Related Proteus Syndrome (PS) PS is characterized by progressive segmental or ...

... et al. Histogenesis of vascular tumors in the Proteus syndrome. South Med J. 1994 Feb; 87 (2):228– ... Gulhan Y, Cakan T, et al. Anaesthesia for Proteus syndrome. Eur J Anaesthesiol. 2000 Oct; 17 (10):645– ...

... not assoc w/↑ risk for embryonal tumors. AKT1 Proteus syndrome See footnote 3. Asymmetric overgrowth, vascular malformations incl ... Cowden syndrome, Bannayan-Riley-Ruvalcaba syndrome, PTEN -related Proteus syndrome, & PTEN -related Proteus-like syndrome) AD Asymmetric overgrowth ...

... change in a related gene) is associated with Proteus syndrome [ Lindhurst et al 2011 ]. 2. Deletions resulting in ... a de novo PTEN pathogenic variant. PTEN -related Proteus syndrome and Proteus-like syndrome are also autosomal dominant ...

... Disorder Overlapping w/PROS Differentiating from PROS AKT1 Proteus syndrome NA (somatic) Focal somatic overgrowth, epidermal nevi, vascular ... risk factors in PIK3CA-related overgrowth spectrum and Proteus syndrome. Am J Med Genet C Semin Med Genet. ...

... s) Disorder MOI Clinical Characteristics / Comment AKT1 1 Proteus syndrome See footnote 1. Hamartomatous overgrowth of multiple tissues, ... identified in more than 90% of individuals meeting Proteus syndrome diagnostic criteria. There are no confirmed occurrences of ...

... include Cowden syndrome, Bannayan-Riley-Ruvalcaba syndrome, PTEN -Proteus syndrome, and Proteus-like syndrome. 9. Caux et al [2007] , Tan et al [ ...