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  1. Prostate Cancer, Nutrition, and Dietary Supplements (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK83261
    ... resolved when the study supplements were taken with food. No serious toxicity or adverse events were reported in the study.[ 14 ] References Thomas R, Williams M, Sharma H, et al.: ...