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11 results
  1. ... proposal that cancer cells, like trophoblasts, arise from primordial germ cells . Dr. Beard also thought that some of these ... and cancer cells have a common origin in primordial germ cells. Dr. Kelley maintained, furthermore, that cancer was initiated ...
  2. ... Extracranial Germ Cell Tumors (GCTs) GCTs arise from primordial germ cells, which migrate during embryogenesis from the yolk sac ... GCTs. Figure 1. Extracranial germ cell development from primordial germ cells. Credit: Thomas Olson, M.D. Incidence Childhood GCTs ...
  3. ... cell theory proposes that CNS GCTs arise from primordial germ cells that have aberrantly migrated and undergone malignant transformation. ... without; P = .02).[ 31 ] Global hypomethylation that mirrors primordial germ cells in early development has also been observed in ...
  4. ... make induced pluripotent stem cells (iPSC) differentiate into primordial germ cells and ultimately sperm [Author, personal communication]. Search ClinicalTrials. ...
  5. ... visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Genes Dev. 2004 Aug ...
  6. ... to the trophoblastic theory, all cancers arise from primordial germ cells , some of which become dispersed throughout the body ...
  7. ... hormone production. Because of their greater complement of primordial ... germ cell function maintained in boys. Important concepts related to ...
  8. ... reproductive potential (e.g., semen analysis in men, primordial follicle count ... patients with germ cell tumors, orchiectomy or oophorectomy may reduce germ cell ...
  9. ... cancer develops not in epithelial cells but in germ cells, which are precursors to egg cells, or in ... function of certain cell types, including reproductive cells (germ cells), early blood cells (hematopoietic stem cells), white blood ...
  10. ... instability Microcephaly Sloping forehead PCNT Microcephalic osteo dysplastic primordial dwarfism type II AR High-pitched voice Disproportionate ... a pathogenic variant that is present in the germ [gonadal] cells only.) The family history of some individuals diagnosed ...