Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Search help
6 results
  1. Hypohidrotic Ectodermal Dysplasia - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK1112
    ... Hidrotic ectodermal dysplasia 2 AD Sparse hair or alopecia Normal sweating ability, palmoplantar hyperkeratosis Normal teeth Nail dystrophy Photophobia HOXC13 Ectodermal dysplasia ...
  2. Epidermolysis Bullosa Simplex - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK1369
    ... associated with perioral cracking and cheilitis, hypotrichosis or alopecia, and a painful and ... Peeling skin disorders with skin fragility include acral ...
  3. xmlghr-summaries.xml 
    https://medlineplus.gov/download/ghr-summaries.xml
    ... of the hands and soles of the feet (palmoplantar hyperkeratosis); areas of the skin, especially over the joints, ... other type, NPS-type, do not have extensive palmoplantar hyperkeratosis but do have hyperkeratosis on other areas of ...
  4. Kindler Syndrome - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK349072
    ... childhood and usually decreasing after adolescence), poikiloderma, diffuse palmoplantar hyperkeratosis, and pseudosyndactyly. Mucosal manifestations are also common and ...
  5. Dyskeratosis Congenita and Related Telomere Biology Disorders - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK22301
    ... TBD include epiphora, loss of dermatoglyphics, early graying, palmoplantar hyperkeratosis, eyelash loss, and hair loss from scalp [ Ward ...
  6. Pachyonychia Congenita - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK1280
    ... prematurely leaving a gently sloping distal region of hyperkeratosis and exposed distal finger tip Focal palmoplantar keratoderma usually presents during the first few years ...