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  1. Varicose and other vein problems - self-care 
    https://medlineplus.gov/ency/patientinstructions/000615.htm
    ... you may have: Varicose veins Swelling in your legs Skin changes or even a skin ulcer (sore) in your lower legs These problems may ...
  2. MedlinePlus Drug Information: Nilotinib 
    https://medlineplus.gov/druginfo/meds/a608002.html
    ... are taking a medication for indigestion, heartburn, or ulcers such as cimetidine (Tagamet), famotidine (Pepcid, in Duexis), ... weaknesschest pain or discomfortproblems walking or speakingnumbnesschange in leg skin colorpain or cold sensation in legsstomach pain with ...