... syndrome (HOS) is characterized by upper-limb defects, congenital heart ... or absent thumb(s) to phocomelia. Other upper-limb malformations can ...

... Strabismus Skeletal anomalies Typical facial features Dermatoglyphic ... thumb malformations w/out hypoplasia of the radius AD = autosomal ...

... bones; a personal and/or family history of congenital heart malformation, ... thumb is often absent or hypoplastic in this condition. ...

... an extra digit or digits anywhere between the thumb and fifth finger). Mesoaxial polydactyly is much less common than postaxial polydactyly. Congenital heart disease (CHD). Cardiac malformations that have been described at least once in ...

... proximal insertion of the thumbs, shortening of the thumbs and the first metacarpals, ... malformations (e.g., patent ductus arteriosus, atrial septal defect, ...

... may require eye surgery. Radial ray malformations. Severe malformations of ... for a congenital heart defect, is standard. A cardiologist can assist ...

... CHDs most commonly involving the septum Upper-limb malformations may be unilateral, ... septal defect; CHD = congenital heart disease; CoA = coarctation of the aorta; ID = ...

... Radii (7%): absent or hypoplastic (only with abnormal thumbs), absent or weak pulse Hands ... Microcephaly (20%) Ophthalmic (20%): microphthalmia, cataracts, ...

... extension of the entire distal phalanx of the thumb beyond the ulnar border of the hand when ... malformations of the cervical vertebrae and cervical spine instability, ...

... PubMed : 4726108 ] 184. Karfik V. Further development of congenital malformations influenced by surgical treatment. Acta Univ Carol Med ... MA, Huff DS, DiGeorge AM. The association of congenital malformations and malignant tumors in infants and children. Ann ...