- ... p34). NONO in inv(X;p11.2;q12). CLTC in t(X;17)(p11;q23). Another less-common translocation subtype, t(6;11)(p21;q12), involving a TFEB gene fusion, induces overexpression of TFEB. The translocations involving TFE3 ...
- ... window Gene Fusion Partner Chromosome Location Frequency of Gene Fusion NPM-ALK 5q36.1 ~80% TPM3-ALK 1p23 ~15% ALO17-ALK 17q25.3 Rare ATIC-ALK 2q35 Rare CLTC-ALK 17q23 Rare MSN-ALK Xp11.1 Rare ...
- ... examines two major mechanisms of prostate carcinogenesis: ERG gene fusion/translocation and the loss of the PTEN tumor ... cancer aggressiveness and long-term patient prognosis. ERG gene fusions are found in 40% of primary prostate cancers ...
3 results