... microarray is favored when performing longitudinal assessment of clonal percentage. Deletion/ duplication analysis. Monosomy 7 can be detected by ...

... is associated with monosomy 7 and most 7q deletions. Clonal amplifications of chromosome 3q26-q29 were reported in ...

... Three alterations involved BRAF (V600E, V600D, and one deletion/insertion ... mutation allele frequencies. Another report also described ...

... the L group.[ 1 ] LCH results from the clonal proliferation of immunophenotypically and functionally immature, morphologically rounded ... cells, known for many years to be a clonal proliferation, have now been shown to likely derive ...

... of morphology and immunophenotype, which confirm the characteristic clonal population. In a database analysis, for up to ... T-cell markers (CD4 and CD7) and have clonal rearrangements of their T-cell receptor genes. These ...

... Biology and Cytogenetics of CML CML is a clonal disorder that is usually easily diagnosed because the ... phase disease, durable responses and suppression of cytogenetic clonal evolution have been reported.[ 3 , 4 ] When cytarabine ...

... cells usually express surface immunoglobulin, most bearing a clonal surface immunoglobulin M with either kappa or lambda ... are common and may not represent the same clonal disease.[ 6 ] Immunologic correction through allogeneic SCT is ...

... two-hit” hypothesis,[ 6 , 7 ] in which the clonal origin or first transformed cell of the tumor ... normal, or wild-type, VHL allele, creating a clonal neoplastic cell of origin, which may proliferate into ...

... at risk is possible. Genomic alterations including duplications/deletions ... may demonstrate clonal findings that are not representative of the fetal ...