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32 results
  1. Nutrition and hydration - The Prevention and Management of Pressure Ulcers in Primary and Secondary Care - NCBI ... 
    https://www.ncbi.nlm.nih.gov/books/NBK333165
    ... of life 5.2.5.1.11. Ornithine alpha-ketoglutarate versus placebo One study (n=160) showed there is potentially no clinical difference between ornithine alpha-ketoglutarate and placebo for rate of complete healing of ...
  2. Management of heel pressure ulcers - The Prevention and Management of Pressure Ulcers in Primary and Secondary Care - ... 
    https://www.ncbi.nlm.nih.gov/books/NBK333136
    ... of life 12.1.5.1.4. Ornithine alpha-ketoglutarate versus placebo One study (n=160) showed there is potentially no clinical difference between ornithine alpha-ketoglutarate and placebo for rate of complete healing of ...
  3. SLC25A19-Related Thiamine Metabolism Dysfunction - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK1365
    ... a finding in other genetically defined microcephaly syndromes. Alpha-ketoglutarate. Among other genetic malformation syndromes, a similar level ... DLD Dihydrolipoamide dehydrogenase deficiency AR ↑ levels of urinary alpha-ketoglutarate may be seen in persons w/pathogenic variants ...
  4. xmlghr-summaries.xml 
    https://medlineplus.gov/download/ghr-summaries.xml
    ... or third month of life. A compound called alpha-ketoglutaric acid can be detected in their urine (alpha-ketoglutaric ... disease</synonym><synonym >Familial hyperlysinemia</synonym><synonym ... disease</synonym><synonym >Saccharopine dehydrogenase deficiency ...
  5. Forest plots - The Prevention and Management of Pressure Ulcers in Primary and Secondary Care - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK333147
    ... vs placebo – all cause mortality Figure 180. Ornithine alpha-ketoglutarate vs placebo – time to complete healing Figure 181. Ornithine alpha-ketoglutarate vs placebo – mean% reduction in ulcer size Figure ...
  6. Childhood Cancer Genomics (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK374260
    ... a novel enzymatic activity that promotes conversion of alpha-ketoglutarate to 2-hydroxyglutarate.[ 363 , 364 ] This novel activity ... IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 17 (3): 225- ...
  7. Nuclear Gene-Encoded Leigh Syndrome Spectrum Overview - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK320989
    ... glycosylation defect Riley et al [2017] α-KGDH = alpha-ketoglutarate dehydrogenase; AR = autosomal recessive; BCAA = branched-chain amino ... Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase. Orphanet J Rare Dis. 2013; 8 :192. [ ...
  8. Childhood Acute Myeloid Leukemia Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK66019
    ... a novel enzymatic activity that promotes conversion of alpha-ketoglutarate to 2-hydroxyglutarate.[ 187 , 188 ] This novel activity ... IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 17 (3): 225- ...
  9. Maple Syrup Urine Disease - GeneReviews® - NCBI Bookshelf 
    https://www.ncbi.nlm.nih.gov/books/NBK1319
    ... of BCKD is shared with the pyruvate and alpha-ketoglutarate dehydrogenase complexes, and MSUD type 3 is characterized by increased urinary excretion of BCKAs and alpha-ketoglutarate accompanied by elevated plasma concentrations of lactate, pyruvate, ...
  10. GJB1 Disorders: Charcot-Marie-Tooth Neuropathy (CMT1X) and Central Nervous System Phenotypes - GeneReviews® - NCBI ... 
    https://www.ncbi.nlm.nih.gov/books/NBK1374
    ... recessive disorder acute reversible leukoencephalopathy with increased urinary alpha-ketoglutarate (ARLIAK) (OMIM 618384 ), caused by biallelic pathogenic variants ...
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