... only into early childhood.Two other forms of Tay-Sachs disease, known as juvenile and late-onset, are rare. Signs and symptoms ... those with the infantile form. Characteristic features of juvenile or late-onset Tay-Saches disease include muscle weakness, loss of muscle coordination (ataxia), ...

... changes are responsible for less severe forms of Tay-Sachs disease, known as the juvenile and late-onset forms, which appear later in life. More About This Health Condition Beta-hexosaminidase A beta-N-Acetylhexosaminidase A Hex A HEXA_HUMAN ... Dersh D, Iwamoto Y, Argon Y. Tay-Sachs disease mutations in HEXA target the alpha chain of ...

... on burden of disease manifestations in late-onset Tay-Sachs and Sandhoff diseases. ... report of juvenile-onset Sandhoff disease presenting with a motor neuron ...

... condition. GM2 gangliosidosis, AB variant Hexosaminidase activator deficiency Tay-Sachs disease, AB variant Genetic Testing Registry: Tay-Sachs disease, ...