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Paget disease
- Paget disease of bone is a disorder that causes bones to grow larger and weaker than normal. Affected bones may be misshapen and easily broken (fractured).The ...
- Juvenile Paget disease is a disorder that affects bone growth. This disease causes bones to be abnormally large, misshapen, and easily broken (fractured).The signs ...
- Inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD) is a condition that can affect the muscles, bones, and brain.The first symptom of IBMPFD is often ...
- ... the SQSTM1 gene have been found to cause Paget disease of bone. Many SQSTM1 gene mutations change single ... to break down bone abnormally. In people with Paget disease of bone, affected bone is broken down and ...
- ... to cause the rare, early-onset form of Paget disease of bone. Both mutations are duplications, which means ... down bone abnormally. In people with early-onset Paget disease of bone, affected bone is broken down and ...
- ... who have inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD). This rare disease causes ... can also include a painful bone condition called Paget disease of bone and a brain condition called frontotemporal ...
- ... gene may increase the risk of developing classic Paget disease of bone, particularly in women. These genetic changes ... TNFRSF11B gene have been found to cause juvenile Paget disease. Each of these mutations greatly reduces the function ...
